Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | TNF | P01375 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575414 | 0.83 | ALDH1A1 (0.56) | HSP90AA1MAPTHTTMAOBMAOA | |
| SCHEMBL28575415 | 0.83 | ALDH1A1 (0.56) | HSP90AA1MAPTHTTMAOBMAOA | |
| SCHEMBL624667 | 0.81 | MAPT (0.53) | MAPK1NPC1HSP90AA1MAPTHTT | |
| SCHEMBL625784 | 0.80 | KMT2A (0.57) | RAB9AMAOBMAOAGSK3BMIF | |
| SCHEMBL625104 | 0.76 | DYRK1A (0.60) | MAPK1NPC1MAPTHTTRAB9A | |
| SCHEMBL625103 | 0.76 | DYRK1A (0.60) | MAPK1NPC1MAPTHTTRAB9A | |
| SCHEMBL625559 | 0.74 | MAOB (0.42) | MAPK1NPC1MAPTHTTRAB9A | |
| SCHEMBL624231 | 0.73 | MAPK1 (0.45) | MAPK1NPC1HSP90AA1MAPTHTT | |
| SCHEMBL27850501 | 0.73 | KMT2A (0.40) | MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL28587111 | 0.69 | EGFR (0.50) | MAPK1NPC1HSP90AA1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |