Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | ODC1 | P11926 | 2/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487659 | 1.00 | FDPS (0.33) | FDPSODC1NAALAD2 | |
| SCHEMBL19461382 | 0.95 | ODC1 (0.35) | FDPSODC1NAALAD2 | |
| SCHEMBL4485263 | 0.95 | ODC1 (0.35) | FDPSODC1NAALAD2 | |
| SCHEMBL7924611 | 0.74 | ODC1 (0.37) | FDPSODC1NAALAD2 | |
| SCHEMBL6567609 | 0.74 | ODC1 (0.37) | FDPSODC1NAALAD2 | |
| SCHEMBL2823239 | 0.74 | ODC1 (0.37) | FDPSODC1NAALAD2 | |
| SCHEMBL10659088 | 0.74 | ODC1 (0.37) | FDPSODC1NAALAD2 | |
| SCHEMBL30410707 | 0.71 | NAALAD2 (0.47) | FDPSODC1NAALAD2 | |
| SCHEMBL18428165 | 0.69 | FDPS (0.33) | FDPSODC1 | |
| SCHEMBL10912285 | 0.69 | ODC1 (0.42) | FDPSODC1NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021875-A1 | PEPTIDOMIMETIC MACROCYCLES WITH TRIAZOLE LINKERS | AILERON THERAPEUTICS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| EP-2334697-A1 | PEPTIDOMIMETIC MACROCYCLES | Aileron Therapeutics, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010034031-A1 | PEPTIDOMIMETIC MACROCYCLES | AILERON THERAPEUTICS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |