SCHEMBL625795

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL625794	1.00	TRPV3 (0.62)	TRPV3NR1I2OPRM1OPRL1PDE2A
	SCHEMBL14893654	0.89	NR1I2 (0.51)	TRPV3NR1I2OPRM1OPRL1PDE2A
	SCHEMBL625365	0.89	NR1I2 (0.51)	TRPV3NR1I2OPRM1OPRL1PDE2A
	SCHEMBL624676	0.88	TRPV3 (0.64)	TRPV3NR1I2MAPTKDM4EKCNA5
	SCHEMBL14894282	0.87	TRPV3 (0.50)	TRPV3NR1I2OPRM1OPRL1AHR
	SCHEMBL625314	0.86	TRPV3 (0.61)	TRPV3NR1I2OPRM1OPRL1TLR7
	SCHEMBL14894544	0.86	NR1I2 (0.72)	TRPV3NR1I2OPRM1OPRL1TLR7
	SCHEMBL14894075	0.86	NR1I2 (0.72)	TRPV3NR1I2OPRM1OPRL1TLR7
	SCHEMBL14893437	0.86	NR1I2 (0.53)	TRPV3NR1I2OPRM1OPRL1PDE2A
	SCHEMBL625376	0.85	TRPV3 (0.43)	TRPV3NR1I2OPRM1OPRL1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.