SCHEMBL625365

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14893638	0.93	NR1I2 (0.49)	NR1I2TRPV3HRH3PDE2AOPRM1
	SCHEMBL625794	0.89	TRPV3 (0.62)	NR1I2TRPV3HRH3PDE2AOPRM1
	SCHEMBL625795	0.89	TRPV3 (0.62)	NR1I2TRPV3HRH3PDE2AOPRM1
	SCHEMBL624975	0.86	TRPV3 (0.52)	NR1I2TRPV3OPRM1OPRL1TP53
	SCHEMBL625279	0.86	TRPV3 (0.53)	NR1I2TRPV3OPRM1OPRL1TP53
	SCHEMBL14893654	0.85	NR1I2 (0.51)	NR1I2TRPV3HRH3PDE2AOPRM1
	SCHEMBL624525	0.85	NR1I2 (0.72)	NR1I2TRPV3PDE2ATLR7EPHX2
	SCHEMBL624516	0.84	TRPV3 (0.58)	NR1I2TRPV3HRH3OPRM1OPRL1
	SCHEMBL14893698	0.83	NR1I2 (0.55)	NR1I2TRPV3HRH3OPRM1OPRL1
	SCHEMBL14894282	0.83	TRPV3 (0.50)	NR1I2TRPV3OPRM1OPRL1AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.