Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1873058 | 0.89 | ALDH1A1 (0.44) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL18006706 | 0.84 | TAAR1 (0.47) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL625883 | 0.82 | PNMT (0.56) | PNMTTAAR1TSHRHRH3IDO1 | |
| SCHEMBL23360881 | 0.79 | LOXL2 (0.38) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL24636832 | 0.77 | TAAR1 (0.42) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL111874 | 0.77 | PNMT (0.56) | PNMTTAAR1TSHRHRH3IDO1 | |
| SCHEMBL2528801 | 0.76 | ALDH1A1 (0.55) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL2464280 | 0.72 | ALDH1A1 (0.54) | PNMTTAAR1ALDH1A1TSHRHRH3 | |
| SCHEMBL625739 | 0.72 | CYP2C9 (0.51) | CYP2C9NOS1TACR1MAP2 | |
| SCHEMBL14464883 | 0.71 | PNMT (0.46) | PNMTTAAR1IDO1CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |