Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CD38 | P28907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2988970 | 0.99 | NCF1 (0.44) | NCF1KDM4EASPHRIOX2KDM8 | |
| SCHEMBL6141854 | 0.87 | MITF (0.44) | KDM4EMAPTRAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2993538 | 0.86 | MITF (0.43) | KDM4EMAPTRAB9AMEN1KMT2A | |
| SCHEMBL7563743 | 0.83 | ALDH1A1 (0.44) | KDM4EMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL2988960 | 0.82 | NOS1 (0.40) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL6141834 | 0.80 | MITF (0.35) | ABCB1CYP19A1 | |
| Hydrochloric Acid SCHEMBL2996463 | 0.79 | MITF (0.34) | CYP19A1 | |
| SCHEMBL5522100 | 0.79 | MAPT (0.51) | NCF1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL2979013 | 0.78 | ALDH1A1 (0.36) | PRUNE1ALDH1A1 | |
| SCHEMBL6141882 | 0.78 | GAA (0.50) | KDM4EASPHKDM8MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226107-B1 | N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES | WELLA AG (DE) | 2005-10-05 | — | — | EP | disclosed |