Bicarbonate

Bicarbonate

SCHEMBL6258274

COC(C)OC.O=C(O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
SLC1A3 P43003 1/20 0.38
SLC1A2 P43004 1/20 0.38
SLC1A1 P43005 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.33
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SLC7A5 Q01650 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
CA14 Q9ULX7 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL10711426 0.90 FFAR3 (0.47) TP53SLC1A3SLC1A2SLC1A1SMN1; SMN2
Bicarbonate SCHEMBL9815646 0.86 TSHR (0.33) TP53SLC1A3SLC1A2SLC1A1TSHR
Acetone SCHEMBL593191 0.86 LMNA (0.43) TP53SLC1A3SLC1A2SLC1A1SMN1; SMN2
Lactic Acid SCHEMBL28158392 0.84 TP53 (0.65) TP53SLC1A3SLC1A2SLC1A1TSHR
Alanine SCHEMBL5676883 0.82 SLC1A3 (0.48) TP53SLC1A3SLC1A2SLC1A1ALDH1A1
Dimethylcarbate SCHEMBL6824434 0.82 SLC1A3 (0.32) TP53SLC1A3SLC1A2SLC1A1TSHR
Alanine SCHEMBL5676881 0.82 SLC1A3 (0.48) TP53SLC1A3SLC1A2SLC1A1ALDH1A1
Methyl Alcohol SCHEMBL3869122 0.81
SCHEMBL1153 0.80
SCHEMBL11615697 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0968181-B1 PERFLUORYNATED SULPHONE SALTS, AND THEIR USES AS IONIC CONDUCTION MATERIALS ACEP INC (CA) 2005-04-27 EP claimed
JP-7029598-A None JP disclosed
CN-112072072-A Pre-cycled silicon electrode 通用汽车环球科技运作有限责任公司 2020-12-11 CN disclosed
EP-1581375-A1 FLEXIBLE MOLD, METHOD OF MANUFACTURING SAME AND METHOD OF MANUFACTURING FINE STRUCTURES 3M Innovative Properties Company (US) 2005-10-05 EP disclosed
WO-2004062870-A1 FLEXIBLE MOLD, METHOD OF MANUFACTURING SAME AND METHOD OF MANUFACTURING FINE STRUCTURES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-29 WO disclosed
JP-H0729598-A SECONDARY BATTERY TORAY IND INC 1995-01-31 JP disclosed
EP-0282576-A1 NON-AQUEOUS ELECTROCHEMICAL CELL DURACELL INTERNATIONAL INC. (US) 1988-09-21 EP disclosed
WO-1988002188-A1 NON-AQUEOUS ELECTROCHEMICAL CELL DURACELL INTERNATIONAL INC. (US) 1988-03-24 WO disclosed