Dimethylcarbate

Dimethylcarbate

SCHEMBL6824434

CN(C)C(=O)O.COC(C)OC

nearest known ligand 0.33

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL349574 0.83 TSHR (0.33) ALDH1A1TSHRCHRNB2CHRNA4
Bicarbonate SCHEMBL6258274 0.82 TP53 (0.39) SLC1A3SLC1A2SLC1A1TP53ALDH1A1
Acetic Acid SCHEMBL10711426 0.79 FFAR3 (0.47) SLC1A3SLC1A2SLC1A1TP53ALDH1A1
Acetone SCHEMBL593191 0.76 LMNA (0.43) SLC1A3SLC1A2SLC1A1TP53ALDH1A1
Dimethylcarbate SCHEMBL15360 0.74
Dimethylcarbate SCHEMBL1232328 0.74
Lactic Acid SCHEMBL28158392 0.74 TP53 (0.65) SLC1A3SLC1A2SLC1A1TP53TSHR
SCHEMBL1785595 0.74 CHRNB2 (0.38) TSHRCHRNB2CHRNA4
SCHEMBL9464855 0.74 CHRNB2 (0.35) ALDH1A1CHRNB2CHRNA4
Alanine SCHEMBL5676881 0.72 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004080979-A1 NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES LG LIFE SCIENCES LTD. (KR) 2004-09-23 WO claimed
WO-2004080979-A1 NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES LG LIFE SCIENCES LTD. (KR) 2004-09-23 WO disclosed