Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10843781 | 0.81 | CHRNB4 (0.47) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL1169205 | 0.80 | KMT2A (0.44) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL12862897 | 0.80 | LOXL2 (0.41) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL1168091 | 0.79 | ADRA2A (0.42) | CHRNB4CHRNA3ALDH1A1TSHRGAA | |
| SCHEMBL12877492 | 0.78 | CHRNB4 (0.40) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL1168402 | 0.77 | POLB (0.50) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL1168282 | 0.77 | VCAM1 (0.42) | TDP1CHRNB4CHRNA3ALDH1A1TSHR | |
| SCHEMBL9571113 | 0.77 | CHRNB4 (0.44) | TDP1CHRNB4CHRNA3ALDH1A1CYP3A4 | |
| SCHEMBL12862887 | 0.76 | PNMT (0.45) | CHRNB4CHRNA3ALDH1A1TSHRGAA | |
| SCHEMBL11549727 | 0.76 | KDM4E (0.43) | CHRNB4CHRNA3ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585489-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004058203-A2 | AGENT FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (US) | 2004-07-15 | — | — | WO | disclosed |