SCHEMBL6258947

SCHEMBL6258947

c1ccc(C2=Nc3ccccc3CN2c2ccccc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.65
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HPGD P15428 1/20 0.44
CCR3 P51677 1/20 0.43
LMNA P02545 2/20 0.42
CTSD P07339 1/20 0.41
EGFR P00533 1/20 0.40
ACHE P22303 6/20 0.39
BCHE P06276 2/20 0.39
HRH4 Q9H3N8 1/20 0.39
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28192152 0.91 SIGMAR1 (0.58) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28192155 0.89 SIGMAR1 (0.56) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28192173 0.89 SIGMAR1 (0.56) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28561721 0.89 SIGMAR1 (0.56) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28324632 0.89 SIGMAR1 (0.53) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28324685 0.89 SIGMAR1 (0.53) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28192141 0.87 SIGMAR1 (0.54) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28854194 0.85 SIGMAR1 (0.52) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL6040419 0.83 SIGMAR1 (0.54) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28325741 0.79 SIGMAR1 (0.55) SIGMAR1NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107417628-A Diaryl quianzolinones, its preparation method and its medical usage and the pharmaceutical composition comprising such compound 中国人民解放军军事医学科学院毒物药物研究所 2017-12-01 CN claimed
CN-110372611-A A kind of method of the polysubstituted dihydroquinazoline ketone of selectivity synthesis or quinazolinone 常熟理工学院 2019-10-25 CN disclosed
CN-107417628-A Diaryl quianzolinones, its preparation method and its medical usage and the pharmaceutical composition comprising such compound 中国人民解放军军事医学科学院毒物药物研究所 2017-12-01 CN disclosed
CN-103087477-B Polymer matrix electroluminescent materials and devices 住友化学株式会社 2017-04-12 CN disclosed
EP-1072614-B1 Method for polymerizing vinyl monomers in a coated reactor SHINETSU CHEMICAL CO (JP) 2005-07-06 EP disclosed
EP-0934955-B1 Polymerization process characterized by a two layer coating against scale formation deposited using a steam carrier SHINETSU CHEMICAL CO (JP) 2003-04-16 EP disclosed
US-6362291-B1 PRETREATING VESSEL HAS ANTIDEPOSIT COATING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-03-26 US disclosed
US-6335403-B1 ANTISCALING AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-01-01 US disclosed
US-6320001-B1 COATING INNER WALL SURFACES WITH A POLYMER SCALE PREVENTIVE FILM OF AN AROMATIC OR HETEROCYCLIC COMPOUND HAVING 5 OR MORE CONJUGATED PI BONDS DYE AND/OR PIGMENT ON THE FIRST LAYER AND A SECOND LAYER OF A DYE AND/OR PIGMENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-11-20 US disclosed
EP-0872903-B1 Method for making hydrogen storage alloy powder and electrode comprising the alloy powder SHINETSU CHEMICAL CO (JP) 2001-10-04 EP disclosed
US-4395471-A BUTYL METHACRYLATE-STYRENE COPOLYMER AND A COPPER PHTHALOCYANINE, AND A AZOBENZIDENE XEROX CORPORATION (US) 1983-07-26 US disclosed
EP-0046398-A2 Electrostatographic developer composition XEROX CORPORATION (US) 1982-02-24 EP disclosed
US-4312932-A RESIN PARTICLES CONTAINING UP TO FOUR PIGMENTS AND SINGLE CARRIER XEROX CORPORATION (US) 1982-01-26 US disclosed
US-4147540-A Color electrophotographic developer system employing one carrier having a coating of resin and copper tetra-4-(octadecylsulfonomido)phthalocyanine XEROX CORPORATION (US) 1979-04-03 US disclosed
US-4073965-A SULFONAMIDO PHTHALOCYANINE TONER RESINS XEROX CORPORATION (US) 1978-02-14 US disclosed
US-4066563-A COPPER-TETRA-4-(OCTADECYLSULFONOMIDO) PHTHALOCYANINE ELECTROPHOTOGRAPHIC CARRIER XEROX CORPORATION (US) 1978-01-03 US disclosed
US-4063946-A Electrophotographic color reproduction process employing photoconductive material with dual light fatigue properties RANK XEROX LTD. (EN) 1977-12-20 US disclosed
US-4058397-A ELECTROGRAPHY, DISAZO DYE, COPPER TETRA-4-(OCTADECYL SULFONAMIDO) PHTHALOCYANINE XEROX CORPORATION (US) 1977-11-15 US disclosed
US-4057426-A ELECTROSTATIC, 2,9-DIMETHYL-QUINACRIDONE, COPPER TETRA-4-(OCTADECYLSULFONAMIDO) PHTHALOCYANINE XEROX CORPORATION (US) 1977-11-08 US disclosed
US-3963486-A Electrophotographic imaging process employing epoxy-ester containing liquid developer RANK XEROX LTD. (EN) 1976-06-15 US disclosed