SCHEMBL2979252

SCHEMBL2979252

O=C(CCO)c1cccc(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.59
ALDH1A1 P00352 3/20 0.59
GAA P10253 2/20 0.59
ABL1 P00519 1/20 0.59
POLB P06746 1/20 0.59
ALPI P09923 1/20 0.59
ALPG P10696 1/20 0.59
APEX1 P27695 1/20 0.59
CASP3 P42574 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
CASP7 P55210 1/20 0.59
CASP6 P55212 1/20 0.59
MCL1 Q07820 1/20 0.59
RIN1 Q13671 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
CTNNB1 P35222 1/20 0.55
CA12 O43570 2/20 0.55
CA2 P00918 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28310663 0.89 CTNNB1 (0.53) KDM4EALDH1A1GAAABL1POLB
SCHEMBL4569137 0.84 PARP1 (0.59) KDM4EALDH1A1CTNNB1CA12CA2
SCHEMBL108054 0.83 CA12 (0.59) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL30497947 0.83 CA12 (0.59) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL30666338 0.82 NR4A2 (0.64) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL2026598 0.82 HSD17B3 (0.60) KDM4EALDH1A1GAAL3MBTL1CTNNB1
SCHEMBL4190959 0.82 NR4A2 (0.64) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL29017520 0.82 CTNNB1 (0.54) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL6398443 0.82 CA12 (0.57) KDM4EALDH1A1GAACTNNB1CA12
SCHEMBL14277039 0.81 PARP1 (0.60) KDM4EALDH1A1CTNNB1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US claimed
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction BIODERM RESEARCH (US) 2008-10-16 US claimed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US claimed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US claimed
US-20060074108-A1 Matrix metalloprotease (MMP) inhibitors and their application in cosmetic and pharmaceutical composition BIODERM RESEARCH (US) 2006-04-06 US claimed
US-20050271608-A1 Skin whitening compositions based on hydroxyaryl alkyl ketones and their isosteric derivatives GUPTA SHYAM K 2005-12-08 US claimed
US-8227426-B2 Chiral complexes of ascorbic acid with natural antioxidant and anti-inflammatory ketones including aloe, citrus, ginger, and mango for skin and hair care ISLAND KINETICS INC. (US) 2012-07-24 US disclosed
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care ISLAND KINETICS INC. (US) 2011-03-10 US disclosed
US-7834210-B2 Hair loss prevention by natural amino acid and peptide complexes BIODERM RESEARCH (US) 2010-11-16 US disclosed
US-7777073-B2 Topical delivery system for antiaging and skin whitening agents BIODERM RESEARCH (US) 2010-08-17 US disclosed
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes BIODERM RESEARCH (US) 2009-10-08 US disclosed
US-7572933-B2 Skin and hair restoration by natural amino acid peptide complexes BIODERM RESEARCH (US) 2009-08-11 US disclosed
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites BIODERM RESEARCH (US) 2009-05-21 US disclosed
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles BIODERM RESEARCH (US) 2008-10-16 US disclosed
US-7427690-B2 Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration BIODERM RESEARCH (US) 2008-09-23 US disclosed
US-20080139507-A1 Method of Treating Skin Condition Including Acne, Skin Aging, Body Odor & Diaper Rash by Zinc Zeolite Clathrates BIODERM RESEARCH (US) 2008-06-12 US disclosed
US-20070099886-A1 Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration BIODERM RESEARCH (US) 2007-05-03 US disclosed
US-5876851-A PROTECTIVE COATING ON METAL TEIJIN LIMITED (JP) 1999-03-02 US disclosed
EP-0653455-B1 FILM FOR METAL LAMINATION TEIJIN LTD (JP) 1997-10-01 EP disclosed
EP-0653455-A1 FILM FOR METAL LAMINATION TEIJIN LIMITED (JP) 1995-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110059907-A1 Chiral Complexes of Ascorbic Acid with Natural Antioxidant and Anti-Inflammatory Ketones Including Aloe, Citrus, Ginger, and Mango for Skin and Hair Care GLA, LPO, PLOD3 KDM4E 1594/4885ALDH1A1 110/4885GAA 123/4885
US-20090130154-A1 Topical Delivery of Biological and Cosmetic Agents by Zeolites TYR, MMP1, MMP17 KDM4E 1764/4885ALDH1A1 1967/4885GAA 31/4885
US-20080254130-A1 Skin Antiaging & Brightening via Multi-function Treatment of Enzyme Dysfunction PSMB1, PLOD3, CUTA KDM4E 513/4885ALDH1A1 330/4885GAA 130/4885
US-20090253668-A1 Hair Loss Prevention by Natural Amino Acid and Peptide Complexes MMP1, MMP17, MMP13 KDM4E 3063/4885ALDH1A1 1360/4885GAA 754/4885
US-20080255228-A1 Ascorbic Acid Complexes for Skin Care Including Treatment of Dark Skin & Wrinkles PROC, COL1A1, CUTA KDM4E 1689/4885ALDH1A1 35/4885GAA 365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.