Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260991 | 0.82 | VCAM1 (0.52) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4402565 | 0.80 | VCAM1 (0.63) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30811551 | 0.78 | VCAM1 (0.74) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL239454 | 0.78 | VCAM1 (0.74) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL5313733 | 0.77 | MAPK1 (0.56) | ALDH1A1LMNAMAPTMAPK1MEN1 | |
| SCHEMBL51755 | 0.77 | LMNA (0.72) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16950942 | 0.76 | VCAM1 (0.71) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6259886 | 0.76 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL8282155 | 0.76 | VCAM1 (0.57) | VCAM1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL1806187 | 0.75 | VCAM1 (0.74) | VCAM1ALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005072741-A1 | ((11-OXO-10,11-DIHYDRODIBENZO [B, F] [1, 4] OXAZEPIN-1-YL)OXY) ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS CARDIOVASCULAR PREPARATIONS USED TO TREAT ARTERIOLOSCLEROSIS | BAYER HEALTHCARE AG (DE) | 2005-08-11 | — | — | WO | disclosed |