Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214400 | 0.87 | WNT3A (0.40) | ALDH1A1HPGDSMN1; SMN2LMNAMEN1 | |
| SCHEMBL6214332 | 0.87 | TP53 (0.44) | TP53ALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL7248437 | 0.86 | MAPK1 (0.47) | TP53ALDH1A1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL6211817 | 0.83 | MEN1 (0.41) | ALDH1A1MAPK1LMNARAB9AMEN1 | |
| SCHEMBL6260264 | 0.81 | WNT3A (0.43) | ALDH1A1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6214919 | 0.78 | KMT2A (0.43) | ALDH1A1MAPK1SMN1; SMN2LMNARAB9A | |
| SCHEMBL6216108 | 0.71 | POLB (0.39) | TP53ALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL6212381 | 0.70 | MEN1 (0.46) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| SCHEMBL6214920 | 0.70 | ERN1 (0.47) | TP53ALDH1A1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL6216155 | 0.69 | TRPV1 (0.44) | HPGDSMN1; SMN2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |