Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212836 | 0.87 | ERN1 (0.42) | ERN1MAPTSMN1; SMN2TP53LMNA | |
| SCHEMBL6241375 | 0.82 | WNT3A (0.49) | SMN1; SMN2TP53WNT3AMEN1KMT2A | |
| SCHEMBL6214332 | 0.82 | TP53 (0.44) | SMN1; SMN2TP53LMNAWNT3AMEN1 | |
| SCHEMBL6212859 | 0.78 | DRD2 (0.45) | WNT3AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6215690 | 0.73 | WNT3A (0.47) | SMN1; SMN2TP53WNT3AMEN1KMT2A | |
| SCHEMBL6240064 | 0.72 | WNT3A (0.44) | MAPTTP53LMNAHTR2CWNT3A | |
| SCHEMBL6214253 | 0.72 | ALDH1A1 (0.47) | MAPTSMN1; SMN2LMNARECQLMEN1 | |
| SCHEMBL6210132 | 0.72 | POLB (0.43) | MAPTTP53HTTMEN1KMT2A | |
| SCHEMBL6798524 | 0.71 | LMNA (0.45) | ERN1MAPTSMN1; SMN2LMNAHTR2C | |
| SCHEMBL6216155 | 0.71 | TRPV1 (0.44) | MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |