Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.37 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241375 | 0.85 | WNT3A (0.49) | WNT3ACCNT1CDK9GAAHTR6 | |
| SCHEMBL6214400 | 0.81 | WNT3A (0.40) | WNT3AGAAHTTMAPTSMN1; SMN2 | |
| SCHEMBL6260425 | 0.81 | TP53 (0.39) | GAAHTTANO1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6211817 | 0.80 | MEN1 (0.41) | WNT3AHTTMAPTANO1KDM4E | |
| SCHEMBL6215690 | 0.74 | WNT3A (0.47) | WNT3AGAANAMPTSMN1; SMN2KDM4E | |
| SCHEMBL6216155 | 0.72 | TRPV1 (0.44) | MAPTSMN1; SMN2 | |
| SCHEMBL6216108 | 0.71 | POLB (0.39) | CCNT1CDK9CA1CA2SMN1; SMN2 | |
| SCHEMBL6214919 | 0.70 | KMT2A (0.43) | GAASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6209953 | 0.69 | WNT3A (0.42) | WNT3ACCNT1CDK9HTR6MAPT | |
| SCHEMBL6214920 | 0.69 | ERN1 (0.47) | WNT3AGAAHTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |