SCHEMBL6260923

SCHEMBL6260923

O=C(c1ccccc1)n1nnnc1S

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 5/20 0.53
AMY1A P0DUB6 5/20 0.53
GAA P10253 5/20 0.53
SI P14410 5/20 0.53
MGAM2 Q2M2H8 5/20 0.53
KMT2A Q03164 4/20 0.53
HPGD P15428 3/20 0.53
F2 P00734 3/20 0.53
SLC9A1 P19634 1/20 0.53
MAPT P10636 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ELANE P08246 3/20 0.41
DAGLA Q9Y4D2 1/20 0.41
F12 P00748 3/20 0.41
P2RX4 Q99571 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29433322 0.69 MGAM (1.00) MGAMAMY1AGAASIMGAM2
SCHEMBL2493561 0.69 MGAM (1.00) MGAMAMY1AGAASIMGAM2
SCHEMBL496975 0.66 ELANE (0.70) MGAMAMY1AGAASIMGAM2
Methyl Alcohol SCHEMBL9412646 0.64 ALDH1A1 (0.49) KMT2AHPGDMAPTALDH1A1HTT
SCHEMBL705048 0.64 F2 (0.46) MGAMAMY1AGAASIMGAM2
SCHEMBL918756 0.64 NOTUM (0.47) MGAMAMY1AGAASIMGAM2
SCHEMBL8088255 0.63 ALDH1A1 (0.52) KMT2AHPGDMAPTCYP1A2CYP2C9
SCHEMBL2415227 0.63 ALDH1A1 (0.52) KMT2AHPGDMAPTCYP1A2CYP2C9
Bromide SCHEMBL8976833 0.62 ALDH1A1 (0.50) KMT2AHPGDMAPTCYP1A2CYP2C9
SCHEMBL13731712 0.61 HPGD (0.45) MGAMAMY1AGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881536-B1 Dual-coated radiographic elements with limited hydrophilic colloid coating coverages EASTMAN KODAK CO (US) 2005-11-02 EP disclosed
US-5955249-A HIGH BROMIDE TABULAR GRAIN EMULSION LAYER A 1-(P-ALKOXYPHENYL)-5-MERCAPTOTETRAZOLE TO INCREASE COVERING POWER. EASTMAN KODAK COMPANY (US) 1999-09-21 US disclosed
US-5876913-A Dual-coated radiographic elements with limited hydrophilic colloid coating coverages EASTMAN KODAK COMPANY (US) 1999-03-02 US disclosed
EP-0881536-A1 Dual-coated radiographic elements with limited hydrophilic colloid coating coverages EASTMAN KODAK COMPANY (US) 1998-12-02 EP disclosed
US-5800976-A BLUE TINTED FILM WITH SUPPORT, SILVER HALIDE EMULSION, GELATIN AND SENSITIZERS FOR SILVER COATING AND POWER ENHANCING COMPOUND EASTMAN KODAK COMPANY (US) 1998-09-01 US disclosed
US-5759759-A Radiographic elements exhibiting increased covering power and colder image tones EASTMAN KODAK COMPANY (US) 1998-06-02 US disclosed