Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SI | P14410 | 3/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13731712 | 0.71 | HPGD (0.45) | F2KMT2AHPGDMGAMAMY1A | |
| Hydrochloric Acid SCHEMBL9958956 | 0.69 | HPGD (0.44) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL11220245 | 0.69 | MAPT (0.61) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL20448840 | 0.69 | HPGD (0.42) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL11009351 | 0.67 | ELANE (0.64) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL496975 | 0.67 | ELANE (0.70) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL2578137 | 0.67 | F2 (0.46) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL11285194 | 0.67 | ELANE (0.44) | F2KMT2AHPGDMGAMAMY1A | |
| SCHEMBL135362 | 0.67 | ELANE (0.60) | F2ELANEPLAUALDH1A1KLKB1 | |
| SCHEMBL5579308 | 0.63 | POLB (0.57) | GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325176-B1 | Process for the preparation of Isoxazolin-3-yl-Acylbenzenes | BASF SE (DE) | 2015-02-25 | — | — | EP | disclosed |
| EP-2298749-B1 | Process for the preparation of Thioethers | BASF SE (DE) | 2014-12-24 | — | — | EP | disclosed |
| CN-101679284-B | 4-(4-trifluoromethyl-3-thiobenzoyl)pyrazoles, and use thereof as herbicides | BAYER CROPSCIENCE AG | 2013-03-27 | — | — | CN | disclosed |
| US-8124810-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2012-02-28 | — | — | US | disclosed |
| US-8049017-B2 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2011-11-01 | — | — | US | disclosed |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | RHEINHEIMER JOACHIM | 2011-06-23 | — | — | US | disclosed |
| EP-2325176-A1 | Process for the preparation of isoxazolin-3-yl-acylbenzenes | BASF SE (DE) | 2011-05-25 | — | — | EP | disclosed |
| EP-2298749-A1 | Process for the preparation of Thioethers | BASF SE (DE) | 2011-03-23 | — | — | EP | disclosed |
| CN-101113137-B | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG | 2010-12-29 | — | — | CN | disclosed |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | BASF SE (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-1852424-A2 | Method for manufacturing isoxazoline-3-yL-acyl benzoles | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-07 | — | — | EP | disclosed |
| US-20070161800-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2007-07-12 | — | — | US | disclosed |
| EP-1077955-B1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| CN-1255377-C | Intermediate for preparing isoxazoline-3-yl acyl benzene and process for preparing intermediate | BASF AG (DE) | 2006-05-10 | — | — | CN | disclosed |
| CN-1757634-A | Intermidiate for preparing 1,2-oxygen nitrogen heterocyclic-2-alkene acylbenzene and its preparation | BASF AG (DE) | 2006-04-12 | — | — | CN | disclosed |
| CN-1495158-A | Intermediate for preparing isoxazoline-3-yl acyl benzene and process for preparing intermediate | �����ɷ� | 2004-05-12 | — | — | CN | disclosed |
| CN-1139578-C | Preparation of isoxazolin-3-yl-acylbenzenes | �����ɷ� | 2004-02-25 | — | — | CN | disclosed |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | BASF SE (DE) | 2003-11-20 | — | — | US | disclosed |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | BASF SE (DE) | 2003-01-23 | — | — | US | disclosed |
| CN-1300284-A | Preparation of isoxazolin-3-yl-acylbenzenes | BASF AG (DE) | 2001-06-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161800-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | CBR3, UQCRB, CYP4X1 | F2 401/4885KMT2A 2028/4885HPGD 1339/4885 |
| US-20110152535-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | F2 305/4885KMT2A 2171/4885HPGD 1423/4885 |
| US-20100105920-A1 | PREPARATION OF ISOXAZOLIN-3-YLACYLBENZENES | CBR3, CYP4X1, UQCRB | F2 305/4885KMT2A 2171/4885HPGD 1423/4885 |
| US-20030216580-A1 | Preparation of Isoxazolin-3-Ylacylbenzene | UQCRB, CYP1B1, CYP2F1 | F2 639/4885KMT2A 1465/4885HPGD 2063/4885 |
| US-20030018200-A1 | Preparation of isoxazolin-3-ylacylbenzenes | CYP2F1, UQCRB, CYP1B1 | F2 674/4885KMT2A 1837/4885HPGD 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.