Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 16/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626464 | 0.89 | MAPT (0.47) | THRBMAPTGAAPIK3CA | |
| SCHEMBL627373 | 0.88 | MAP3K12 (0.46) | THRBMAPTPIK3CA | |
| SCHEMBL625621 | 0.86 | MAP3K12 (0.46) | MAPTPIK3CA | |
| SCHEMBL625746 | 0.86 | PIK3CA (0.54) | NEK2PIK3CA | |
| SCHEMBL627411 | 0.85 | MAP3K12 (0.47) | MAPTPIK3CA | |
| SCHEMBL625132 | 0.84 | CKS1B (0.42) | THRBMAPTRXFP1GAAPIK3CA | |
| SCHEMBL624968 | 0.84 | MAP3K12 (0.43) | THRBMAPTGAAPIK3CA | |
| SCHEMBL624412 | 0.83 | MAP3K12 (0.45) | MAPTPIK3CA | |
| SCHEMBL625188 | 0.82 | CKS1B (0.44) | THRBMAPTGAAPIK3CA | |
| SCHEMBL625228 | 0.82 | MAP3K12 (0.46) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |