SCHEMBL6261102

SCHEMBL6261102

CC(F)C(F)(F)N1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7086526 0.69 PARL (0.30)
SCHEMBL28449846 0.67
SCHEMBL28663684 0.67
SCHEMBL29202816 0.65
SCHEMBL2754568 0.64 LMNA (0.33)
SCHEMBL12386592 0.64 BRD4 (0.32)
SCHEMBL18712300 0.62 PIK3CD (0.35) PIK3CD
SCHEMBL11886130 0.60 MEN1 (0.41) PIK3CD
SCHEMBL28537874 0.60
SCHEMBL24564940 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005037281-A1 1-ALKYLPIPERAZINYL-PYRROLIDIN-2, 5-DIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONIST RANBAXY LABORATORIES LIMITED (IN) 2005-04-28 WO claimed
WO-2005037281-A1 1-ALKYLPIPERAZINYL-PYRROLIDIN-2, 5-DIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONIST RANBAXY LABORATORIES LIMITED (IN) 2005-04-28 WO disclosed