SCHEMBL28537874

SCHEMBL28537874

O=C1CCC(=S)N1C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29202816 0.82
SCHEMBL7086526 0.82 PARL (0.30)
SCHEMBL28449846 0.79
SCHEMBL9863926 0.76
SCHEMBL25317166 0.63 POLB (0.47)
SCHEMBL168847 0.62
SCHEMBL22651309 0.62
SCHEMBL23500212 0.62
SCHEMBL6261102 0.60 PIK3CD (0.32)
SCHEMBL4955196 0.60 PARL (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608260-A Method for synthesizing aromatic vinyl trifluoro-methyl sulfide compound by removing boric acid 江南大学 2021-04-06 CN claimed
CN-115583902-A Preparation method of alkynyl thioether compound 江苏医药职业学院 2023-01-10 CN disclosed
CN-112608260-B Method for synthesizing aromatic vinyl trifluoro-methyl sulfide compound by removing boric acid 江南大学 2022-06-10 CN disclosed
CN-112608260-A Method for synthesizing aromatic vinyl trifluoro-methyl sulfide compound by removing boric acid 江南大学 2021-04-06 CN disclosed