SCHEMBL626138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL624598	0.85	TRPV3 (0.52)	TRPV3KDM4ENR1I2KCNA5KCNE1
	SCHEMBL625770	0.85	TRPV3 (0.43)	TRPV3KDM4ENR1I2KCNA5KCNE1
	SCHEMBL626095	0.83	TRPV3 (0.46)	TRPV3KDM4ENR1I2KCNA5KCNE1
	SCHEMBL626384	0.79	TRPV3 (0.43)	TRPV3KDM4ENR1I2KCNA5TP53
	SCHEMBL625133	0.79	TRPV3 (0.48)	TRPV3NR1I2KCNA5KCNH2LMNA
	SCHEMBL14895928	0.76	TRPV3 (0.48)	TRPV3NR1I2KCNA5TP53
	SCHEMBL14893921	0.76	TRPV3 (0.46)	TRPV3NR1I2CYP3A4
	SCHEMBL625818	0.76	TRPV3 (0.43)	TRPV3KDM4ENR1I2CYP1A2LMNA
	SCHEMBL624839	0.75	TRPV3 (0.55)	TRPV3KDM4ENR1I2KCNA5KCNE1
	SCHEMBL626330	0.73	TRPV3 (0.48)	TRPV3NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.