Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 19/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.48 |
| ▸ | MAST3 | O60307 | 4/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265215 | 0.82 | BTK (0.58) | ADORA3TMIGD3 | |
| SCHEMBL6264936 | 0.79 | MAPK8 (0.58) | MAPK8ADORA3TMIGD3 | |
| SCHEMBL6262920 | 0.78 | POLB (0.45) | MAPK8 | |
| SCHEMBL6262086 | 0.77 | SYK (0.60) | MAPK8MAST3 | |
| SCHEMBL6264925 | 0.76 | MAPK8 (0.57) | MAPK8ADORA3TMIGD3MAST3MAPK9 | |
| SCHEMBL6260383 | 0.76 | SYK (0.59) | MAPK8ADORA3TMIGD3 | |
| SCHEMBL6268219 | 0.74 | MAPK8 (0.52) | MAPK8MAST3MAPK9 | |
| SCHEMBL6260435 | 0.74 | SYK (0.61) | MAPK8ADORA3TMIGD3MAST3 | |
| SCHEMBL6260272 | 0.74 | MAPK8 (0.49) | MAPK8MAST3MAPK9 | |
| SCHEMBL6264246 | 0.73 | AURKA (0.60) | MAPK8ADORA3TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005085252-A1 | IMIDAZO ‘1,2-A’ PYRAZINE COMPOUNDS WHICH INTERACT WITH PROTEIN KINASES | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-09-15 | — | — | WO | claimed |