Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.46 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628243 | 0.83 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627199 | 0.82 | FYN (0.46) | FYNHASPINMKNK1 | |
| SCHEMBL627017 | 0.80 | FYN (0.47) | FYNHASPIN | |
| SCHEMBL627849 | 0.80 | FYN (0.46) | FYNHASPINPIM1MKNK1 | |
| SCHEMBL627167 | 0.79 | FYN (0.46) | FYNHASPIN | |
| SCHEMBL627106 | 0.76 | FYN (0.44) | FYNHASPIN | |
| SCHEMBL626604 | 0.74 | FYN (0.35) | FYNHASPINPIM1 | |
| SCHEMBL627111 | 0.74 | LMNA (0.33) | LMNATHRB | |
| SCHEMBL625300 | 0.72 | PIK3CA (0.51) | FYNHASPIN | |
| SCHEMBL2257059 | 0.71 | MKNK1 (0.63) | FYNHASPINPIM1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |