Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028119 | 0.87 | ALDH1A1 (0.69) | POLBRAB9AALDH1A1GAACYP1A2 | |
| SCHEMBL22065282 | 0.86 | POLB (0.56) | POLBRAB9AALDH1A1MAPK1TSHR | |
| SCHEMBL10659662 | 0.86 | POLB (0.56) | POLBCYP3A4RAB9AALDH1A1MAPK1 | |
| SCHEMBL11596592 | 0.84 | ALDH1A1 (0.71) | POLBRAB9AALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13662282 | 0.84 | POLB (0.79) | POLBCYP3A4RAB9AALDH1A1MAPK1 | |
| SCHEMBL9645123 | 0.83 | CYP3A4 (0.56) | POLBCYP3A4RAB9AALDH1A1NR4A1 | |
| SCHEMBL3800184 | 0.82 | MAPT (0.54) | POLBRAB9AALDH1A1GAAMAPT | |
| SCHEMBL11320359 | 0.82 | GNG2 (0.53) | POLBRAB9AALDH1A1MAPK1MAPT | |
| SCHEMBL2855474 | 0.82 | TDP1 (0.52) | POLBCYP3A4RAB9AALDH1A1GAA | |
| SCHEMBL11691760 | 0.81 | CYP3A4 (0.73) | POLBCYP3A4RAB9AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540817-A | Process for the preparation of 5-amino-2,4-dimethylacetanilide | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-10 | — | — | US | claimed |
| EP-0054809-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-2,4 DIMETHYLACETANILIDE | BAYER AG (DE) | 1984-05-23 | — | — | EP | claimed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | claimed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2005025498-A2 | SUBSTITUTED ACETANILIDES AND BENZAMIDES FOR THE TREATMENT OF ASTHMA AND PULMONARY INFLAMMATION | CORUS PHARMA (US) | 2005-03-24 | — | — | WO | disclosed |
| US-6399820-B2 | PLACING A NUCLEOPHILE, WHOSE NUCLEOPHILIC ATOM IS ADVANTAGEOUSLY A NITROGEN, IN CONTACT WITH A SULPHONYL HALIDE AND AN ORGANIC BASE | RHODIA CHIMIE (FR) | 2002-06-04 | — | — | US | disclosed |
| US-20010020113-A1 | Process and reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function | DESMURS JEAN-ROGER (FR) | 2001-09-06 | — | — | US | disclosed |
| US-6271419-B1 | Process and reagent useful for the synthesis of sulphanilide which is perhalogenated on the carbon borne by the sulphur atom of the sulphanilide function | RHODIA CHIMIE (FR) | 2001-08-07 | — | — | US | disclosed |
| EP-0338986-B1 | PLANT GROWTH INHIBITING AGENT | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0338986-A2 | Plant growth inhibiting agent | CIBA-GEIGY AG (CH) | 1989-10-25 | — | — | EP | disclosed |
| EP-0242850-A1 | Water soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-28 | — | — | EP | disclosed |
| EP-0054809-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-2,4 DIMETHYLACETANILIDE | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| EP-0054809-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-2,4 DIMETHYLACETANILIDE | BAYER AG (DE) | 1984-05-23 | — | — | EP | disclosed |
| US-4380464-A | HERBICIDES AND PLANT GROWTH REGULATORS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-04-19 | — | — | US | disclosed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0054809-A1 | Process for the preparation of 5-amino-2,4 dimethylacetanilide | BAYER AG (DE) | 1982-06-30 | — | — | EP | disclosed |
| EP-0048551-A1 | N,N-diacylaminoperfluoroalkanesulfonanilides and derivatives thereof | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1982-03-31 | — | — | EP | disclosed |
| US-4013444-A | Inhibiting grass growth with 5-acetamido-2,4-dimethyltrifluoromethanesulfonanilide | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4007213-A | Process for preparing 1-(N-β-cyanethylaminol-3-acylaminobenzenes | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | POLB 1436/4885CYP3A4 725/4885RAB9A 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.