Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262103 | 0.86 | POLB (0.56) | POLBALOX15USP2CASP1CASP7 | |
| SCHEMBL11028119 | 0.83 | ALDH1A1 (0.69) | POLBLMNAALDH1A1MAPTGAA | |
| SCHEMBL3800184 | 0.82 | MAPT (0.54) | POLBALOX15USP2CASP1CASP7 | |
| SCHEMBL11320359 | 0.82 | GNG2 (0.53) | POLBALOX15LMNAALDH1A1MAPT | |
| SCHEMBL2855474 | 0.82 | TDP1 (0.52) | POLBALOX15USP2CASP1CASP7 | |
| SCHEMBL11596592 | 0.81 | ALDH1A1 (0.71) | POLBLMNAALDH1A1MAPTCA1 | |
| SCHEMBL2081736 | 0.80 | TDP1 (0.57) | POLBHSD17B10ALDH1A1MAPTCA1 | |
| SCHEMBL6827233 | 0.80 | KIF11 (0.52) | POLBALOX15USP2CASP1CASP7 | |
| SCHEMBL30483162 | 0.80 | TDP1 (0.57) | POLBHSD17B10ALDH1A1MAPTCA1 | |
| SCHEMBL11317896 | 0.80 | EPHX2 (0.58) | POLBUSP2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3663293-A1 | SUBSTITUTED PENTA- AND HEXA-HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, DRUG COMBINATION AND USE THEREOF | Xiamen University (CN) | 2020-06-10 | — | — | EP | disclosed |