Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969938 | 0.83 | CA12 (0.51) | KMT2AMEN1HSP90AA1CHRNB2CHRNB4 | |
| SCHEMBL31277918 | 0.80 | PDE10A (0.47) | KMT2AHTR1ADRD2KCNH2NQO2 | |
| SCHEMBL4872932 | 0.80 | DRD2 (0.52) | KMT2AMEN1HSP90AA1DRD2CHRNB2 | |
| SCHEMBL8019874 | 0.80 | KDM1A (0.49) | HTR1AKDM1APNMTADRA2AALDH1A1 | |
| SCHEMBL10155714 | 0.80 | HSP90AA1 (0.44) | KMT2AMEN1HSP90AA1CHRNB2CHRNB4 | |
| SCHEMBL6260142 | 0.79 | HTR1A (0.43) | HTR1ADRD2KCNH2NQO2MTNR1A | |
| SCHEMBL484623 | 0.78 | HTR1A (0.43) | HTR1ADRD2KCNH2NQO2MTNR1A | |
| SCHEMBL18221710 | 0.77 | HTR1A (0.42) | HTR1ADRD2KCNH2NQO2MTNR1A | |
| SCHEMBL9630654 | 0.76 | MTNR1A (0.65) | KDM1ANQO2MTNR1AMTNR1B | |
| SCHEMBL599005 | 0.76 | MTNR1A (0.57) | KMT2AMEN1MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005084205-A2 | DIAMINO THIAZOLOINDAN DERIVATIVES AND THEIR USE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2005-09-15 | — | — | WO | disclosed |
| US-20050197365-A1 | Diamino thiazoloindan derivatives and their use | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2005-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197365-A1 | Diamino thiazoloindan derivatives and their use | RTN3, RTN4, DRD4 | KMT2A 3723/4885MEN1 2240/4885HSP90AA1 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.