Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL600649 | 0.98 | F2 (0.46) | ADRB2F2TMPRSS4TP53CYP1A2 | |
| SCHEMBL24152552 | 0.82 | ALDH1A1 (0.55) | ADRB2TSHRPDE2ACNR1ALDH1A1 | |
| SCHEMBL24810807 | 0.82 | ALDH1A1 (0.50) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL1186051 | 0.80 | ALDH1A1 (0.62) | ADRB2TSHRALDH1A1CA2CA1 | |
| SCHEMBL8248221 | 0.80 | ALDH1A1 (0.62) | ADRB2TSHRALDH1A1CA2CA1 | |
| SCHEMBL8182080 | 0.80 | ENPP2 (0.48) | ADRB2PDE2ACNR1ALDH1A1KDM4E | |
| SCHEMBL311851 | 0.80 | ENPP2 (0.48) | ADRB2PDE2ACNR1ALDH1A1KDM4E | |
| SCHEMBL1790668 | 0.80 | ALDH1A1 (0.62) | ADRB2TSHRALDH1A1CA2CA1 | |
| SCHEMBL14211437 | 0.80 | ENPP2 (0.48) | ADRB2PDE2ACNR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL2352018 | 0.78 | ALDH1A1 (0.60) | ADRB2TSHRALDH1A1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050123591-A1 | Wound coverings for removal of interfering factors from wound fluid | BEIERSDORF AG | 2005-06-09 | — | — | US | claimed |
| EP-0878551-B1 | Enhancement of the factor-VII sensitivity of a thromboplastin reagent | DADE BEHRING MARBURG GMBH (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20020197257-A1 | Wound coverings for removal of interfering factors from wound fluid | BEIERSDORF AG | 2002-12-26 | — | — | US | claimed |
| US-20020018802-A1 | Wound coverings for removal of interfering factors from wound fluid | MEYER-INGOLD WOLFGANG (DE) | 2002-02-14 | — | — | US | claimed |
| US-20020012958-A1 | INCREASING THE FVII SENSITIVITY OF A THROMBOPLASTIN REAGENT | DADE BEHRING MARBURG GMBH (DE) | 2002-01-31 | — | — | US | claimed |
| EP-0878551-A2 | Enhancement of the factor-VII sensitivity of a thromboplastin reagent | Dade Behring Marburg GmbH (DE) | 1998-11-18 | — | — | EP | claimed |
| US-20250152677-A1 | TREATMENT OF LIVER CANCERS BY DISRUPTING THE BETA-CATENIN/TCF-4 BINDING SITE LOCATED UPSTREATM OF MEG3 IN THE DLK1/DIO3 LOCUS | INOVARION (FR) | 2025-05-15 | — | — | US | disclosed |
| EP-4479534-A1 | TREATMENT OF LIVER CANCERS BY DISRUPTING THE BETA-CATENIN/TCF-4 BINDING SITE LOCATED UPSTREAM OF MEG3 IN THE DLK1/DIO3 LOCUS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023152351-A1 | TREATMENT OF LIVER CANCERS BY DISRUPTING THE BETA-CATENIN/TCF-4 BINDING SITE LOCATED UPSTREAM OF MEG3 IN THE DLK1/DIO3 LOCUS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2023-08-17 | — | — | WO | disclosed |
| EP-2603079-B1 | POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 | MERCK SHARP & DOHME (US) | 2018-09-19 | — | — | EP | disclosed |
| EP-2721029-B1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME (US) | 2018-07-18 | — | — | EP | disclosed |
| US-9315518-B2 | Imidazopyridin-2-one derivatives | MERCK SHARP & DOHME CORP. (US) | 2016-04-19 | — | — | US | disclosed |
| EP-2705024-B1 | Alkyne benzotriazole derivatives | MERCK SHARP & DOHME (US) | 2015-12-16 | — | — | EP | disclosed |
| US-6376209-B2 | HEAT TREATMENT | DADE BEHRING MARBURG GMBH (DE) | 2002-04-23 | — | — | US | disclosed |
| US-20020012958-A1 | INCREASING THE FVII SENSITIVITY OF A THROMBOPLASTIN REAGENT | DADE BEHRING MARBURG GMBH (DE) | 2002-01-31 | — | — | US | disclosed |
| US-5874298-A | WASP NEUROTOXIN FOR CONTROLLING HELIOTHIS VIRESCENS (TOBACCO BUDWORM); FAST ACTING, INSECTS STOP FEEDING QUICKLY; LOW TOXICITY TO MAMMALS; HOST CELLS AND VECTORS EXPRESSING TOXIN | NPS PHARMACEUTICALS, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| EP-0878551-A2 | Enhancement of the factor-VII sensitivity of a thromboplastin reagent | Dade Behring Marburg GmbH (DE) | 1998-11-18 | — | — | EP | disclosed |
| EP-0812328-A1 | INSECTICIDAL TOXINS FROM BRACON HEBETOR | NPS PHARMACEUTICALS, INC. (US) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996025429-A9 | INSECTICIDAL TOXINS FROM BRACON HEBETOR | — | 1996-12-19 | — | — | WO | disclosed |
| WO-1996025429-A1 | INSECTICIDAL TOXINS FROM BRACON HEBETOR | NPS PHARMACEUTICALS, INC. (US) | 1996-08-22 | — | — | WO | disclosed |