Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.45 |
| ▸ | CA2 known ✓ | P00918 | 7/20 | 0.38 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.38 |
| ▸ | ROCK2 known ✓ | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 known ✓ | Q13464 | 2/20 | 0.36 |
| ▸ | BCHE known ✓ | P06276 | 1/20 | 0.33 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626386 | 0.98 | ADRB2 (0.46) | F2TMPRSS4ADRB2TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL14121049 | 0.81 | ENPP2 (0.46) | ADRB2PDE2ACNR1ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL14157349 | 0.81 | ENPP2 (0.46) | ADRB2PDE2ACNR1ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL14120652 | 0.81 | ENPP2 (0.46) | ADRB2PDE2ACNR1ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL2352018 | 0.81 | ALDH1A1 (0.60) | ADRB2TSHRALDH1A1CA2MAPT | |
| SCHEMBL24152552 | 0.80 | ALDH1A1 (0.55) | ADRB2TSHRPDE2ACNR1ALDH1A1 | |
| SCHEMBL24810807 | 0.80 | ALDH1A1 (0.50) | F2TMPRSS4TP53CYP1A2CYP2D6 | |
| SCHEMBL14211437 | 0.78 | ENPP2 (0.48) | ADRB2PDE2ACNR1ALDH1A1KDM4E | |
| SCHEMBL8248221 | 0.78 | ALDH1A1 (0.62) | ADRB2TSHRALDH1A1CA2CA1 | |
| SCHEMBL1790668 | 0.78 | ALDH1A1 (0.62) | ADRB2TSHRALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028637-A1 | PROMOTERS FOR REGULATION OF GENE EXPRESSION IN PLANTS | SYNGENTA CROP PROTECTION AG (CH) | 2026-01-29 | — | — | US | disclosed |
| US-12428650-B2 | Corn event 5307 | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-30 | — | — | US | disclosed |
| US-12173297-B2 | Promoters for regulation of gene expression in plants | SYNGENTA CROP PROTECTION AG (CH) | 2024-12-24 | — | — | US | disclosed |
| CN-117587059-A | Promoters for regulating gene expression in plants | 先正达农作物保护股份公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20230323386-A1 | CORN EVENT 5307 | SYNGENTA PARTICIPATIONS AG (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20220325293-A1 | PROMOTERS FOR REGULATION OF GENE EXPRESSION IN PLANTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-13 | — | — | US | disclosed |
| EP-4025040-A1 | PROMOTERS FOR REGULATION OF GENE EXPRESSION IN PLANTS | Syngenta Crop Protection AG (CH) | 2022-07-13 | — | — | EP | disclosed |
| US-20210011425-A1 | CORN EVENT 5307 | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| US-20210011424-A1 | CORN EVENT 5307 | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| US-10844400-B2 | Corn event 5307 | SYNGENTA PARTICIPATION AG (CH) | 2020-11-24 | — | — | US | disclosed |
| EP-2289311-A2 | Corn event MIR604 | Syngenta Participations AG. (CH) | 2011-03-02 | — | — | EP | disclosed |
| US-7897748-B2 | Corn event MIR604 | SYNGENTA PARTICIPATIONS AG (CH) | 2011-03-01 | — | — | US | disclosed |
| EP-2281447-A2 | Corn event MIR604 | Syngenta Participations AG. (CH) | 2011-02-09 | — | — | EP | disclosed |
| WO-2010077816-A1 | CORN EVENT 5307 | SYNGENTA PARTICIPATIONS AG (CH) | 2010-07-08 | — | — | WO | disclosed |
| US-20080167456-A1 | Corn Event MIR604 | SYNGENTA PARTICIPATIONS AG (CH) | 2008-07-10 | — | — | US | disclosed |
| US-7361813-B2 | Corn event MIR604 | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| EP-1737290-A4 | CORN EVENT MIR604 | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| EP-1737290-A2 | CORN EVENT MIR604 | Syngeta Participations AG (CH) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005103301-A2 | CORN EVENT MIR604 | SYNGENTA PARTICIPATIONS AG (CH) | 2005-11-03 | — | — | WO | disclosed |
| US-20050216970-A1 | Expression vector comprising nucleotide sequences coding bacterial crystal protein for use in transformation, propagation and generation of rootworm resistant plants; insecticidal protein; biological pest control | SYNGENTA PARTICIPATIONS AG (CH) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028637-A1 | PROMOTERS FOR REGULATION OF GENE EXPRESSION IN PLANTS | RNGTT, PURB, UPF1 | ADRB2 3921/4885CA2 4716/4885GAA 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.