Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6263973 | 0.81 | HPGD (0.68) | RAB9ASMN1; SMN2NPC1TP53NPSR1 | |
| SCHEMBL11333992 | 0.81 | NPC1 (0.55) | RAB9ASMN1; SMN2NPC1TP53NPSR1 | |
| SCHEMBL6245001 | 0.81 | HPGD (0.67) | RAB9ASMN1; SMN2NPC1NPSR1MAPK1 | |
| SCHEMBL9737564 | 0.80 | RAB9A (0.58) | RAB9ASMN1; SMN2NPC1TP53HPGD | |
| SCHEMBL6266686 | 0.77 | NPC1 (0.68) | RAB9ASMN1; SMN2NPC1TP53NPSR1 | |
| SCHEMBL12918768 | 0.74 | SNCA (0.57) | RAB9ASMN1; SMN2NPC1TP53HPGD | |
| SCHEMBL6737766 | 0.72 | NPC1 (0.74) | RAB9ASMN1; SMN2NPC1TP53ALDH1A1 | |
| SCHEMBL8058008 | 0.71 | GPR84 (0.58) | RAB9ASMN1; SMN2NPC1TP53HPGD | |
| SCHEMBL12550898 | 0.71 | KDM4E (0.66) | RAB9ASMN1; SMN2NPC1TP53PTGS2 | |
| SCHEMBL9364714 | 0.71 | ACHE (0.47) | RAB9ASMN1; SMN2NPC1TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |