SCHEMBL626446

SCHEMBL626446

C=CC(C(=O)O)(C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.52
▸ TSHR P16473 1/20 0.52
▸ CYP1A2 P05177 2/20 0.46
▸ HTT P42858 1/20 0.44
▸ AKT1 P31749 1/20 0.41
▸ CYP2D6 P10635 1/20 0.39
▸ KMT2A Q03164 3/20 0.39
▸ MAPT P10636 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.38
▸ CYP2C19 P33261 2/20 0.38
▸ KCNN4 O15554 1/20 0.38
▸ TGM2 P21980 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ KEAP1 Q14145 1/20 0.37
▸ NFE2L2 Q16236 1/20 0.37
▸ HDAC3 O15379 1/20 0.36
▸ HDAC4 P56524 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC7 Q8WUI4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9439081 0.77 ALDH1A1 (0.52) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL27985150 0.77 CYP1A2 (0.52) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL4888619 0.76 TSHR (0.50) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL2928012 0.74 ALDH1A1 (0.48) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL20557179 0.74 ALDH1A1 (0.48) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL8669950 0.72 NPSR1 (0.52) ALDH1A1TSHRCYP1A2HTTCYP2D6
SCHEMBL6554159 0.71 TSHR (0.46) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL20556841 0.70 ALDH1A1 (0.49) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL25430781 0.70 ALDH1A1 (0.44) ALDH1A1TSHRCYP1A2HTTAKT1
SCHEMBL11802484 0.70 ALDH1A1 (0.44) ALDH1A1TSHRCYP1A2HTTAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695461-B2 Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme HENKEL AG & CO. KGAA (DE) 2017-07-04 — — US claimed
US-20140186868-A1 METHOD FOR ADAPTING A HYDROLYTIC ENZYME TO A COMPONENT THAT STABILIZES THE HYDROLYTIC ENZYME HENKEL AG & CO., KGAA (DE) 2014-07-03 — — US claimed
US-4234509-A METAL SALTS OF CARBOXYLIC OR SULFONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-18 — — US claimed
EP-3710568-B1 METHOD OF CLEANING A SURFACE HAVING SOIL COMPRISING FATTY ACID AND CONSUMER PRODUCT COMPOSITION THEREFOR PROCTER & GAMBLE (US) 2024-07-17 — — EP disclosed
US-20230089159-A1 CLEANING COMPOSITION COMPRISING AN ENGINEERED FATTY ACID ALPHA-DIOXYGENASE ALMAC SCIENCES LIMITED (GB) 2023-03-23 — — US disclosed
WO-2023044183-A1 CLEANING COMPOSITION COMPRISING AN ENGINEERED FATTY ACID ALPHA-DIOXYGENASE THE PROCTER & GAMBLE COMPANY (US) 2023-03-23 — — WO disclosed
US-11319510-B2 Method and consumer product composition having enzymes for cleaning a surface having soil comprising fatty acid THE PROCTER & GAMBLE COMPANY (US) 2022-05-03 — — US disclosed
US-20220112446-A1 CLEANING COMPOSITION COMPRISING AN ALPHA-DIOXYGENASE THE PROCTER & GAMBLE COMPANY 2022-04-14 — — US disclosed
WO-2022076334-A2 CLEANING COMPOSITION COMPRISING AN ALPHA-DIOXYGENASE THE PROCTER & GAMBLE COMPANY (US) 2022-04-14 — — WO disclosed
EP-3243897-B2 DETERGENT COMPOSITION COMPRISING AN FATTY ACID-TRANSFORMING ENZYME PROCTER & GAMBLE (US) 2022-02-16 — — EP disclosed
EP-3483251-B1 DETERGENT COMPOSITION COMPRISING FATTY ACID PROCESSING ENZYMES PROCTER & GAMBLE (US) 2021-11-10 — — EP disclosed
US-20170321162-A1 DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY 2017-11-09 — — US disclosed
US-9695461-B2 Method for adapting a hydrolytic enzyme to a component that stabilizes the hydrolytic enzyme HENKEL AG & CO. KGAA (DE) 2017-07-04 — — US disclosed
US-20140186868-A1 METHOD FOR ADAPTING A HYDROLYTIC ENZYME TO A COMPONENT THAT STABILIZES THE HYDROLYTIC ENZYME HENKEL AG & CO., KGAA (DE) 2014-07-03 — — US disclosed
EP-2598621-A2 STABILIZED LIQUID TENSIDE PREPARATION COMPRISING ENZYMES Henkel AG & Co. KGaA (DE) 2013-06-05 — — EP disclosed
EP-2569055-A2 PHOTO-STABILIZING AGENTS Merck Patent GmbH (DE) 2013-03-20 — — EP disclosed
WO-2012019849-A3 STABILIZED LIQUID TENSIDE PREPARATION COMPRISING ENZYMES HENKEL AG & CO. KGAA (DE) 2012-06-07 — — WO disclosed
WO-2012019849-A2 STABILIZED LIQUID TENSIDE PREPARATION COMPRISING ENZYMES HENKEL AG & CO. KGAA (DE) 2012-02-16 — — WO disclosed
WO-2011141110-A2 PHOTO-STABILIZING AGENTS MERCK PATENT GMBH (DE) 2011-11-17 — — WO disclosed
US-4234509-A METAL SALTS OF CARBOXYLIC OR SULFONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089159-A1 CLEANING COMPOSITION COMPRISING AN ENGINEERED FATTY ACID ALPHA-DIOXYGENASE HAO2, HAAO, HAO1 ALDH1A1 174/4885TSHR 4607/4885CYP1A2 185/4885
US-20220112446-A1 CLEANING COMPOSITION COMPRISING AN ALPHA-DIOXYGENASE HAO2, HAO1, AOX1 ALDH1A1 98/4885TSHR 4715/4885CYP1A2 197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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