Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6271790 | 0.82 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6264474 | 0.78 | RAB9A (0.48) | GRM5RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL6269445 | 0.77 | SMN1; SMN2 (0.41) | GRM5RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL6264556 | 0.76 | CASP3 (0.41) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6271503 | 0.74 | ALDH1A1 (0.36) | GRM5RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4181126 | 0.72 | ALDH1A1 (0.47) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6271786 | 0.72 | NPC1 (0.45) | RAB9ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6264160 | 0.70 | ALDH1A1 (0.45) | RAB9ANPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL3986581 | 0.69 | HDAC6 (0.44) | GRM5RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL6268777 | 0.69 | SMN1; SMN2 (0.39) | GRM5RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005095366-A1 | 7-ARYL 1,5-DIHYDRO-4,1-BENZOXAZEPIN-2(3H)-ONE DERIVATIVES AND THEIR USE AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2005-10-13 | — | — | WO | disclosed |