Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261654 | 0.85 | SCN9A (0.35) | P2RY12SCN9APIK3CAMTORMAPK10 | |
| SCHEMBL5692224 | 0.83 | PIK3CA (0.37) | SYKALDH1A1PIK3CAMTORMAPK10 | |
| SCHEMBL5176620 | 0.74 | ALDH1A1 (0.37) | ALDH1A1PIK3CAMTORMAPK10CRHR1 | |
| SCHEMBL5158447 | 0.73 | ALDH1A1 (0.36) | ALDH1A1PIK3CAMTORMAPK10CRHR1 | |
| SCHEMBL15689222 | 0.72 | KDM1A (0.48) | SCN9APIK3CAMTORMAPK10KDM1A | |
| SCHEMBL5486206 | 0.69 | ALDH1A1 (0.37) | ALDH1A1PIK3CAMTORMAPK10CRHR1 | |
| SCHEMBL13167926 | 0.68 | HSP90AA1 (0.39) | LMNAPIK3CAMTOR | |
| SCHEMBL5174949 | 0.68 | PIK3CA (0.38) | LMNAPIK3CAMTOR | |
| SCHEMBL10192200 | 0.67 | PARP1 (0.47) | SCN9AALDH1A1LMNAPIK3CAMTOR | |
| SCHEMBL5691400 | 0.66 | P2RX7 (0.39) | ALDH1A1LMNAPIK3CAMTORMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585488-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | claimed |
| WO-2004058206-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| EP-1585488-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004058206-A1 | NOVEL PHENYLENEDIAMINE DERIVATIVE COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |