Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265164 | 0.86 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| SCHEMBL16596492 | 0.86 | SLC15A1 (0.55) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| Hydrochloric Acid SCHEMBL27518479 | 0.80 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| SCHEMBL6546883 | 0.80 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| Hydrochloric Acid SCHEMBL19511476 | 0.80 | ALDH1A1 (0.59) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| SCHEMBL6157816 | 0.80 | SLC15A1 (0.52) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| SCHEMBL84418 | 0.79 | SLC15A1 (0.63) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL4523936 | 0.79 | SLC15A1 (0.65) | SLC15A1ALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL589202 | 0.79 | SLC15A1 (0.61) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 | |
| SCHEMBL8025769 | 0.79 | ALDH1A1 (0.50) | SLC15A1ALDH1A1MAPK1L3MBTL1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807690-B2 | 2,3-dihydro-iminoisoindole derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-10-05 | — | — | US | disclosed |
| US-20100184981-A1 | 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES | CLARK RICHARD | 2010-07-22 | — | — | US | disclosed |
| EP-2202231-A1 | 2,3-DIHYDROIMINOISOINDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2010-06-30 | — | — | EP | disclosed |
| US-20090270433-A1 | 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184981-A1 | 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES | SERPINC1, F7, F2 | SLC15A1 2248/4885ALDH1A1 1133/4885MAPK1 721/4885 |
| US-20090270433-A1 | 2,3-DIHYDRO-IMINOISOINDOLE DERIVATIVES | SERPINC1, F7, F2 | SLC15A1 2082/4885ALDH1A1 1107/4885MAPK1 715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.