Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265235 | 0.85 | POLB (0.40) | ALOX5HTTCA2ALDH1A1CYP4F2 | |
| SCHEMBL7097815 | 0.83 | MAPT (0.41) | RECQLALDH1A1POLBKMT2ATSHR | |
| SCHEMBL6630242 | 0.82 | POLB (0.36) | ALOX5HTTCA2ALDH1A1CYP4F2 | |
| SCHEMBL1299 | 0.76 | SMN1; SMN2 (0.45) | RECQLCA2ALDH1A1POLBKMT2A | |
| SCHEMBL7098893 | 0.71 | AURKA (0.40) | RECQLALDH1A1POLBKMT2ASOAT1 | |
| SCHEMBL9468529 | 0.71 | SMN1; SMN2 (0.43) | RECQLALDH1A1POLBKMT2ATSHR | |
| SCHEMBL6630708 | 0.69 | ALOX5 (0.38) | ALOX5CA2ALDH1A1POLBKMT2A | |
| SCHEMBL1017 | 0.68 | GRN (0.43) | ALDH1A1POLBLMNAMAPTKDM4E | |
| SCHEMBL6263848 | 0.68 | ALOX5 (0.37) | ALOX5ALDH1A1POLBKMT2ASOAT1 | |
| SCHEMBL4692253 | 0.67 | LMNA (0.46) | ALDH1A1POLBKMT2ATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091940-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-0854142-B1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0854142-A1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |