Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4657455 | 0.82 | TAAR1 (0.36) | IDO1PKMTAAR1ALDH1A1LMNA | |
| SCHEMBL4658455 | 0.81 | GGPS1 (0.42) | IDO1PGRKDM4EPYCR1 | |
| SCHEMBL4657362 | 0.80 | NR3C1 (0.37) | PGRALDH1A1KDM4E | |
| SCHEMBL4714787 | 0.79 | MRGPRX4 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL4657447 | 0.76 | ATM (0.40) | TAAR1EPHX2ALDH1A1LMNA | |
| SCHEMBL6824702 | 0.75 | ALDH1A1 (0.40) | IDO1PNMTPKMTAAR1ALDH1A1 | |
| SCHEMBL6265284 | 0.74 | IDO1 (0.50) | IDO1PNMTPKMTAAR1KCNJ5 | |
| SCHEMBL4658917 | 0.74 | VCAM1 (0.43) | HSD11B1ALDH1A1LMNA | |
| SCHEMBL4658860 | 0.73 | SLC6A4 (0.39) | IDO1TAAR1EPHX2ALDH1A1KDM4E | |
| SCHEMBL4716546 | 0.73 | FDPS (0.40) | IDO1PNMTTAAR1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385817-B1 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-7402691-B2 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-22 | — | — | US | disclosed |
| US-7011838-B2 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-03-14 | — | — | US | disclosed |
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | OTAKA KEN | 2005-09-22 | — | — | US | disclosed |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-1385817-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002090320-A2 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209323-A1 | Malononitrile compounds and their use as pesticides | C1S, C1R, C5 | IDO1 382/4885PNMT 1061/4885PKM 2571/4885 |
| US-20040138065-A1 | Malononitrile compounds and their use as pesticides | CBR1, MAL2, CBR3 | IDO1 278/4885PNMT 779/4885PKM 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.