Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261701 | 1.00 | KIF11 (0.44) | KIF11CETPCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6352729 | 0.99 | KIF11 (0.43) | KIF11CETPCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6353046 | 0.99 | KIF11 (0.43) | KIF11CETPCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6262729 | 0.99 | KIF11 (0.45) | KIF11CETPCYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6351633 | 0.97 | KIF11 (0.44) | KIF11CETPCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6264152 | 0.81 | GRIK1 (0.41) | KIF11 | |
| SCHEMBL6261777 | 0.81 | GRIK1 (0.41) | KIF11 | |
| SCHEMBL6260613 | 0.79 | GRIK1 (0.41) | KIF11 | |
| Hydrochloric Acid SCHEMBL6345432 | 0.79 | GRIK1 (0.41) | KIF11 | |
| SCHEMBL6261457 | 0.79 | GRIK1 (0.41) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317426-B1 | BETA-THIO-AMINO ACIDS | GRUENENTHAL GMBH (DE) | 2005-11-16 | — | — | EP | claimed |
| US-6846843-B2 | Gabapentin; antiepileptic agents, analgesics | GRUENENTHAL GMBH (DE) | 2005-01-25 | — | — | US | claimed |
| US-20030236253-A1 | Beta-thioamino acids | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | claimed |
| US-6846843-B2 | Gabapentin; antiepileptic agents, analgesics | GRUENENTHAL GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20030236253-A1 | Beta-thioamino acids | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236253-A1 | Beta-thioamino acids | TPMT, OPRD1, TST | KIF11 4515/4885CETP 1951/4885CYP1A2 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.