SCHEMBL6265458

SCHEMBL6265458

CCCC(=O)OCCC[SiH](OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.44
NAAA Q02083 1/20 0.40
HTR2C P28335 1/20 0.40
ALDH1A1 P00352 3/20 0.39
DNM1 Q05193 1/20 0.38
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 2/20 0.35
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPT P10636 3/20 0.35
RECQL P46063 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
FAAH O00519 1/20 0.34
EPHX2 P34913 1/20 0.34
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341115 0.79 ALDH1A1 (0.54) NAAAALDH1A1
SCHEMBL421653 0.78 NAAA (0.60) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL5930623 0.78 DGKA (0.60) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL1809600 0.77 HTR2C (0.42) DGKANAAAHTR2CALDH1A1PRSS1
Pentane-1,5-Dibutanoate SCHEMBL15705199 0.76 NAAA (0.64) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL420094 0.76 NAAA (0.64) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL113994 0.76 DGKA (0.64) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL25282181 0.75 DGKA (0.57) DGKANAAAHTR2CALDH1A1DNM1
SCHEMBL8770651 0.75 DGKA (0.57) DGKANAAAHTR2CALDH1A1DNM1
Ammonia Solution, Strong SCHEMBL11778584 0.74 DGKA (0.61) DGKANAAAHTR2CALDH1A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005103061-A1 METHOD OF MANUFACTURING AN ORGANOALKOXYSILANE HAVING ESTER-FUNCTIONAL GROUPS DOW CORNING TORAY CO., LTD. (JP) 2005-11-03 WO disclosed