Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626170 | 0.83 | PIK3CA (0.53) | PIK3CAMAP3K12 | |
| SCHEMBL625674 | 0.82 | PIK3CA (0.50) | PIK3CAMAP3K12 | |
| SCHEMBL625189 | 0.81 | PIK3CA (0.46) | PIK3CAMAP3K12 | |
| SCHEMBL625653 | 0.80 | PIK3CA (0.54) | PIK3CAMAP3K12 | |
| SCHEMBL625235 | 0.80 | FYN (0.52) | PIK3CA | |
| SCHEMBL626579 | 0.79 | PIK3CA (0.56) | PIK3CAMAP3K12 | |
| SCHEMBL626701 | 0.78 | MKNK1 (0.52) | PIK3CA | |
| SCHEMBL625652 | 0.78 | PIK3CA (0.49) | PIK3CAMAP3K12 | |
| SCHEMBL624388 | 0.78 | PIK3CA (0.55) | PIK3CAMAP3K12 | |
| SCHEMBL625434 | 0.75 | PIK3CA (0.50) | PIK3CAMAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |