SCHEMBL6267301

SCHEMBL6267301

C=C(/C=C/C=O)N(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.36
GAPDH P04406 1/20 0.32
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267303 1.00 TRPA1 (0.36) TRPA1GAPDHLMNA
SCHEMBL24244881 0.77 CA12 (0.32)
SCHEMBL27977920 0.73 ABCB11 (0.31)
SCHEMBL608202 0.72
SCHEMBL26496110 0.67
SCHEMBL22914707 0.67
SCHEMBL22754245 0.65 TRPA1 (0.35) TRPA1
SCHEMBL7112680 0.64
Acrolein SCHEMBL3847493 0.64 ZDHHC20 (0.40) TRPA1LMNA
SCHEMBL24228665 0.64 ABCB11 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1434557-B1 AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS HENKEL KGAA (DE) 2005-11-09 EP claimed