Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLB1 | P16278 | 3/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208478 | 0.92 | — | — | |
| SCHEMBL7569033 | 0.84 | — | — | |
| SCHEMBL21011949 | 0.82 | ALDH1A1 (0.44) | CYP1A2ALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL20344863 | 0.80 | — | — | |
| SCHEMBL9830506 | 0.78 | ALDH1A1 (0.41) | CYP1A2ALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL9239822 | 0.77 | GNAO1 (0.42) | ALDH1A1GBA1SPHK1GUSBEPHX1 | |
| SCHEMBL11540777 | 0.77 | GNAO1 (0.42) | ALDH1A1GBA1SPHK1GUSBEPHX1 | |
| SCHEMBL10642680 | 0.76 | — | — | |
| SCHEMBL6400664 | 0.75 | CYP1A2 (0.39) | CYP1A2ALDH1A1GBA1SPHK1GUSB | |
| SCHEMBL10569484 | 0.75 | CYP1A2 (0.62) | CYP1A2ALDH1A1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987500-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20140039215-A1 | 4-Biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-06 | — | — | US | disclosed |
| US-8586783-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20130018202-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2013-01-17 | — | — | US | disclosed |
| US-8168566-B2 | 4-biphenyl-substituted pyrazolidin-3,5-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2012-05-01 | — | — | US | disclosed |
| US-8119566-B2 | use as pesticides and/or herbicides and/or microbicides; for the selective control of weeds; synergistic; low application rates and concentrations; in particular in cereals (especially wheat) | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20120040963-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-6451843-B1 | Arylphenyl-substituted cyclic keto enols | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| US-6417370-B1 | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
| EP-1204638-A1 | BIPHENYL-SUBSTITUTED CYCLIC KETO ENOLS AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2002-05-15 | — | — | EP | disclosed |
| EP-1075465-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO ENOLS | BAYER AG (DE) | 2001-02-14 | — | — | EP | disclosed |
| WO-2001009092-A1 | BIPHENYL-SUBSTITUTED CYCLIC KETO ENOLS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-08 | — | — | WO | disclosed |
| EP-1066258-A1 | ARYL PHENYL SUBSTITUTED CYCLIC KETOENOLS | Bayer Aktiengesellschaft (DE) | 2001-01-10 | — | — | EP | disclosed |
| EP-1056717-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | Bayer Aktiengesellschaft (DE) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999055673-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999048869-A1 | ARYL PHENYL SUBSTITUTED CYCLIC KETOENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |
| WO-1999043649-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039215-A1 | 4-Biphenyl-substituted pyrazolidin-3,5-dione derivatives | DDT, CYP4X1, HPD | CYP1A2 24/4885ALDH1A1 1105/4885GBA1 2759/4885 |
| US-20120040963-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | CYP1A2 24/4885ALDH1A1 1105/4885GBA1 2759/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | CYP1A2 26/4885ALDH1A1 2569/4885GBA1 1407/4885 |
| US-20130018202-A1 | 4-Biphenyl-Substituted Pyrazolidin-3,5-Dione Derivatives | DDT, CYP4X1, HPD | CYP1A2 24/4885ALDH1A1 1105/4885GBA1 2759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.