Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27981521 | 0.86 | HPGDS (0.58) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL5904040 | 0.84 | NR4A2 (0.78) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL2247416 | 0.81 | HDAC6 (0.72) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL5844471 | 0.79 | HPGDS (0.60) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL14292893 | 0.79 | HSD17B2 (0.53) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL420401 | 0.77 | ALOX15 (0.68) | NR4A2LMNAALOX15HDAC1FABP4 | |
| SCHEMBL1761545 | 0.77 | RAB9A (0.92) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL6264976 | 0.76 | ALDH1A1 (0.49) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL6260315 | 0.76 | RAB9A (0.83) | HPGDSMEN1POLBRAB9AKMT2A | |
| SCHEMBL23578834 | 0.75 | MAPT (0.55) | HPGDSHDAC6HSD17B2HSD17B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |