Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774 | 0.91 | SMN1; SMN2 (0.68) | HRH1SMN1; SMN2CYP1A2CYP2C19PARP10 | |
| Hydrochloric Acid SCHEMBL3513717 | 0.89 | SMN1; SMN2 (0.66) | HRH1SMN1; SMN2CYP1A2CYP2C19PARP10 | |
| SCHEMBL7376400 | 0.89 | SMN1; SMN2 (0.61) | HRH1SMN1; SMN2CYP1A2CYP2C19PARP10 | |
| SCHEMBL7378329 | 0.87 | HRH1 (0.64) | HRH1SMN1; SMN2CYP1A2CYP2C19PARP10 | |
| SCHEMBL18248625 | 0.87 | HRH1 (0.64) | HRH1SMN1; SMN2CYP1A2CYP2C19PARP10 | |
| SCHEMBL6446039 | 0.82 | CYP1A2 (0.57) | HRH1SMN1; SMN2CYP1A2CYP2C19TDP1 | |
| SCHEMBL29499090 | 0.82 | SMN1; SMN2 (0.62) | HRH1SMN1; SMN2CYP1A2CYP2C19TDP1 | |
| SCHEMBL333243 | 0.82 | SMN1; SMN2 (0.62) | HRH1SMN1; SMN2CYP1A2CYP2C19TDP1 | |
| SCHEMBL5493166 | 0.81 | SMN1; SMN2 (0.56) | HRH1SMN1; SMN2CYP1A2CYP2C19TDP1 | |
| SCHEMBL403460 | 0.81 | CYP1A2 (0.56) | HRH1SMN1; SMN2CYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116718773-A | Cytokine/chemokine Panel for determining tumor immune loop reconstruction | 奥明（杭州）基因科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| WO-2023110772-A1 | COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING AT LEAST A MEROCYANINE AND A HYDROTROPE | L'OREAL (FR) | 2023-06-22 | — | — | WO | claimed |
| CN-110291068-B | Process for the preparation of 2-pyridylethylcarboxamide derivatives | 拜耳农作物科学股份公司 | 2023-04-11 | — | — | CN | claimed |
| EP-3558945-B1 | PROCESS FOR THE PREPARATION OF A N-[2-(2-PYRIDINYL)ETHYL]CARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10807955-B2 | Process for the preparation of a 2-pyridylethylcarboxamide derivative | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-20 | — | — | US | claimed |
| EP-3634975-A2 | 15.BETA.-[3-PROPANAMIDO]-SUBSTITUTED ESTRA-1,3,5(10)-TRIEN-17-ONE COMPOUNDS AND THEIR 17-OXIMES FOR USE IN INHIBITION OF 17.BETA.-HYDROXYSTEROID DEHYDROGENASES | Forendo Pharma Ltd (FI) | 2020-04-15 | — | — | EP | claimed |
| US-20200039937-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-06 | — | — | US | claimed |
| EP-3558945-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | Bayer CropScience Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | claimed |
| WO-2018224736-A2 | THERAPEUTICALLY ACTIVE STEROIDAL DERIVATIVES | FORENDO PHARMA LTD (FI) | 2018-12-13 | — | — | WO | claimed |
| WO-2018114484-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | claimed |
| JP-2008524307-A | — | — | 2008-07-10 | — | — | JP | claimed |
| EP-1915362-A1 | AMIDE ALKYL PYRIDIYL QUINOLINES AS NK3 RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2008-04-30 | — | — | EP | claimed |
| US-20080086008-A1 | N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; starting with a halogenobenzoyl derivative to produce a N-acetoxymethylcarboxamide derivative and then coupling it with a 2-pyridyl acetate derivative; pesticide | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-04-10 | — | — | US | claimed |
| WO-2007116374-A1 | NOVEL SULFONAMIDE COMPOUNDS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-10-18 | — | — | WO | claimed |
| EP-1831169-A2 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2007-09-12 | — | — | EP | claimed |
| CN-1332942-C | Sulfonylamino-acetic acid derivatives and their use as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-22 | — | — | CN | claimed |
| WO-2007018465-A1 | AMIDE ALKYL PYRIDIYL QUINOLINES AS NK3 RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2007-02-15 | — | — | WO | claimed |
| WO-2006067103-A2 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE SA (FR) | 2006-06-29 | — | — | WO | claimed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | claimed |
| EP-0375451-A2 | Compounds having a renin-inhibiting activity | BEECHAM GROUP PLC (GB) | 1990-06-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807955-B2 | Process for the preparation of a 2-pyridylethylcarboxamide derivative | CPS1, PLPBP, CYP4F2 | HRH1 1114/4885SMN1; SMN2 952/4885CYP1A2 39/4885 |
| US-20080086008-A1 | N-{2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]ethyl}-2-trifluoromethylbenzamide; starting with a halogenobenzoyl derivative to produce a N-acetoxymethylcarboxamide derivative and then coupling it with a 2-pyridyl acetate derivative; pesticide | DDT, PFAS, AADAC | HRH1 4052/4885SMN1; SMN2 1857/4885CYP1A2 27/4885 |
| US-20200039937-A1 | PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE | CPS1, CYP4F2, PLPBP | HRH1 1034/4885SMN1; SMN2 805/4885CYP1A2 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.