Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676889 | 0.89 | KDM4E (0.54) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL9676894 | 0.82 | KDM4E (0.51) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL10624052 | 0.82 | KDM4E (0.51) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL9674405 | 0.73 | KDM4E (0.58) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL9674984 | 0.73 | NPSR1 (0.53) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL9814439 | 0.72 | KDM4E (0.54) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL8855451 | 0.70 | KDM4E (0.51) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL29991189 | 0.69 | MAPT (0.59) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL28390672 | 0.69 | MAPT (0.59) | KDM4EMAPTHPGDPOLBALDH1A1 | |
| SCHEMBL7807160 | 0.69 | MAPT (0.69) | KDM4EMAPTHPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326845-B1 | N-ALKOXYALKYL-SUBSTITUTED BENZIMIDAZOLES AND THE USE THEREOF AS AN AGENT AGAINST PARASITIC PROTOZOANS | BAYER HEALTHCARE AG (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-20040044055-A1 | N-alkoxlyalkyl-substituted benzimidazoles and the use thereof as an agent against parastic protozoans | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-04 | — | — | US | disclosed |
| EP-1326845-A1 | N-ALKOXYALKYL-SUBSTITUTED BENZIMIDAZOLES AND THE USE THEREOF AS AN AGENT AGAINST PARASITIC PROTOZOANS | Bayer Aktiengesellschaft (DE) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002030909-A1 | N-ALKOXYALKYL-SUBSTITUTED BENZIMIDAZOLES AND THE USE THEREOF AS AN AGENT AGAINST PARASITIC PROTOZOANS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044055-A1 | N-alkoxlyalkyl-substituted benzimidazoles and the use thereof as an agent against parastic protozoans | PIGO, EPX, PIGK | KDM4E 1871/4885MAPT 4508/4885HPGD 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.