SCHEMBL6270004

SCHEMBL6270004

O=c1n(CCCCCBr)c(=O)n(CCCCCBr)c(=O)n1CCCCCBr

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
HSP90AA1 P07900 1/20 0.33
TLR9 Q9NR96 1/20 0.33
FAAH O00519 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
XBP1 P17861 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
GPR35 Q9HC97 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
ADORA2B P29275 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268843 1.00 ALDH1A1 (0.33) ALDH1A1NPSR1HSP90AA1TLR9FAAH
SCHEMBL6268427 0.97 RGS4 (0.31) FAAHMGLLADORA2BRGS4
SCHEMBL6265971 0.89 RGS4 (0.32) NPSR1RGS4
SCHEMBL6270653 0.77 CYP3A4 (0.35) NPSR1TP53SMN1; SMN2
SCHEMBL9626274 0.74 MGLL (0.52) ALDH1A1HSP90AA1FAAHLMNATP53
SCHEMBL12787622 0.74 MGLL (0.52) ALDH1A1HSP90AA1FAAHLMNATP53
SCHEMBL13327050 0.74 ALDH1A1 (0.42) ALDH1A1NPSR1HSP90AA1TLR9FAAH
SCHEMBL11840543 0.74 MGLL (0.52) ALDH1A1HSP90AA1FAAHLMNATP53
SCHEMBL4963710 0.74 MGLL (0.52) ALDH1A1HSP90AA1FAAHLMNATP53
SCHEMBL13327054 0.74 ADORA2B (0.37) ALDH1A1NPSR1HSP90AA1TLR9FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed