SCHEMBL6270218

SCHEMBL6270218

CCOC(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 9/20 0.63
NPC1 O15118 7/20 0.63
HPGD P15428 3/20 0.63
CRHBP P24387 1/20 0.63
CRHR2 Q13324 1/20 0.63
MAPT P10636 4/20 0.61
HSD17B10 Q99714 3/20 0.61
LMNA P02545 3/20 0.61
MAPK1 P28482 2/20 0.61
ALDH1A1 P00352 4/20 0.58
CYP1A2 P05177 3/20 0.58
CYP2C19 P33261 3/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 2/20 0.58
HIF1A Q16665 1/20 0.58
CASP3 P42574 2/20 0.58
SENP8 Q96LD8 2/20 0.58
SENP7 Q9BQF6 2/20 0.58
SENP6 Q9GZR1 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822402 0.86 POLB (0.56) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL3823480 0.84 L3MBTL1 (0.58) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL3826853 0.84 RAB9A (0.52) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL11464044 0.84 ALDH1A1 (0.59) RAB9ANPC1HPGDMAPTLMNA
SCHEMBL5404742 0.83 MEN1 (0.66) RAB9ANPC1HPGDMAPTLMNA
SCHEMBL2096821 0.83 RAB9A (0.62) RAB9ANPC1HPGDMAPTALDH1A1
SCHEMBL9792296 0.83 RAB9A (0.63) RAB9ANPC1HPGDMAPTLMNA
SCHEMBL3822534 0.82 RAB9A (0.57) RAB9ANPC1HPGDCRHBPCRHR2
SCHEMBL4432278 0.81 MGLL (0.65) RAB9ANPC1MAPTLMNAALDH1A1
SCHEMBL30207797 0.81 MGLL (0.65) RAB9ANPC1MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107580607-B Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2019-09-27 CN disclosed
CN-107580607-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS 巴塞尔聚烯烃意大利有限公司 2018-01-12 CN disclosed
EP-1069115-B1 PROCESS FOR PRODUCING OXAZOLIDIN-2-ONE DERIVATIVES DAISO CO LTD (JP) 2005-12-07 EP disclosed
US-6271388-B1 REACTING A 1,3-DIOXOLAN-2-ONE DERIVATIVE AND A CARBAMATE DERIVATIVE OR AN UREA DERIVATIVE IN THE PRESENCE OF A FLUORIDE SALT. DAISO CO., LTD. (JP) 2001-08-07 US disclosed
EP-1069115-A1 PROCESS FOR PRODUCING OXAZOLIDIN-2-ONE DERIVATIVES DAISO CO., LTD. (JP) 2001-01-17 EP disclosed
EP-0425209-B1 Naphthyloxazolidone derivatives TANABE SEIYAKU CO (JP) 1995-05-10 EP disclosed
US-5332754-A Antidepressant TANABE SEIYAKU CO., LTD. (JP) 1994-07-26 US disclosed
US-5182296-A Antidepressants TANABE SEIYAKY CO., LTD. (JP) 1993-01-26 US disclosed
EP-0425209-A2 Naphthyloxazolidone derivatives TANABE SEIYAKU CO., LTD. (JP) 1991-05-02 EP disclosed