Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 11/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6762808 | 0.82 | ALOX5AP (0.39) | SCN5ATYK2ADORA3KDM4ENPC1 | |
| SCHEMBL6271045 | 0.77 | ADORA2A (0.45) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6266948 | 0.76 | ALOX5AP (0.39) | SCN5ATYK2KDM4ENPC1ALDH1A1 | |
| SCHEMBL4391246 | 0.76 | TYK2 (0.45) | SCN5ATYK2KDM4ENPC1ALDH1A1 | |
| SCHEMBL2645021 | 0.73 | DYRK1A (0.48) | KDM4EALDH1A1MAPTRAB9ACHRNA7 | |
| SCHEMBL2645408 | 0.67 | ATR (0.45) | CYP1A2ALOX5APFEN1 | |
| SCHEMBL4613467 | 0.66 | TDP2 (0.46) | SCN5ATYK2NPC1ALDH1A1RAB9A | |
| SCHEMBL3664986 | 0.65 | CLK4 (0.57) | SCN5AKDM4ENPC1ALDH1A1GAA | |
| SCHEMBL29628993 | 0.64 | SCN5A (0.54) | SCN5AALDH1A1SCN1ASCN2A | |
| SCHEMBL7696321 | 0.64 | NISCH (0.43) | SCN5ATYK2KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175410-B1 | PESTICIDAL TRIAZINE DERIVATIVES | NOVARTIS AG (CH) | 2005-12-07 | — | — | EP | disclosed |
| US-6723720-B2 | PHENYL-SUBSTITUTED 1,2,4-TRIAZINES, ESPECIALLY FOR CONTROLLING FLEAS | NOVARTIS ANIMAL HEALTH US, INC. | 2004-04-20 | — | — | US | disclosed |
| US-20030036544-A1 | Pesticidal triazine-derivatives | NOVARTIS ANIMAL HEALTH US, INC. | 2003-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036544-A1 | Pesticidal triazine-derivatives | DDT, CYCS, TUBA3C | SCN5A 807/4885TYK2 3815/4885ADORA3 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.