Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | XIAP | P98170 | 4/20 | 0.41 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038814 | 0.84 | AGTR2 (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL4041221 | 0.81 | ALDH1A1 (0.49) | GAAALDH1A1LMNA | |
| SCHEMBL4034993 | 0.80 | CACNA2D1 (0.48) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL4035592 | 0.75 | ALDH1A1 (0.53) | GAAALDH1A1SMN1; SMN2XIAPBIRC3 | |
| SCHEMBL4032376 | 0.73 | ALDH1A1 (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL4037091 | 0.71 | ENPP2 (0.46) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL4032714 | 0.70 | HTR1A (0.44) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL13197309 | 0.68 | XIAP (0.57) | XIAPBIRC3BIRC2 | |
| SCHEMBL17512449 | 0.67 | CACNA2D1 (0.81) | CACNA2D1CACNA1BCACNB1CACNA1CALDH1A1 | |
| SCHEMBL4032488 | 0.67 | POLB (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2ACFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-A2 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004071390-A2 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-08-26 | — | — | WO | disclosed |