Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037027 | 0.70 | ALDH1A1 (0.42) | L3MBTL1MAPK1LMNAATMHPGD | |
| SCHEMBL7528145 | 0.69 | MAPT (0.41) | L3MBTL1KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL17918582 | 0.68 | KMT2A (0.45) | L3MBTL1KDM4EMAPK1TSHRTDP1 | |
| SCHEMBL23479282 | 0.66 | PRCP (0.36) | KDM4EATMALDH1A1HSD17B10NAAA | |
| SCHEMBL16330102 | 0.65 | NAAA (0.47) | LMNATSHRALDH1A1HSD17B10NAAA | |
| Hydrochloric Acid SCHEMBL7363323 | 0.65 | KDM4E (0.47) | KDM4EMAPK1HPGDALDH1A1MAPT | |
| SCHEMBL11881200 | 0.64 | NAAA (0.50) | LMNATSHRALDH1A1NAAA | |
| SCHEMBL2713588 | 0.64 | PRCP (0.51) | ATMHPGDTSHRALDH1A1 | |
| SCHEMBL2638667 | 0.64 | PRCP (0.51) | ATMHPGDTSHRALDH1A1 | |
| SCHEMBL8257937 | 0.64 | PRCP (0.51) | ATMHPGDTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189612-A4 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1189612-A1 | VLA-4 INHIBITOR COMPOUNDS | Daiichi Pharmaceutical Co., Ltd. (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000206-A1 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-04 | — | — | WO | disclosed |