Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527330 | 0.81 | MAPT (0.41) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL4789681 | 0.72 | PNMT (0.49) | ALDH1A1LMNASMN1; SMN2HRH2HSD17B10 | |
| SCHEMBL6270712 | 0.69 | L3MBTL1 (0.34) | MAPTALDH1A1LMNASMN1; SMN2TDP1 | |
| SCHEMBL3391559 | 0.67 | PKM (0.66) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL25845895 | 0.67 | MAPT (0.78) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8304121 | 0.67 | ALDH1A1 (0.41) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL1144551 | 0.66 | MGLL (0.62) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL27818621 | 0.65 | MGLL (0.52) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL27882785 | 0.65 | MGLL (0.60) | MAPTALDH1A1LMNASMN1; SMN2PKM | |
| SCHEMBL11037027 | 0.65 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246847-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | Synaptic Pharmaceutical Corporation (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002002744-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |