Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11623381 | 0.74 | RAB9A (0.50) | HSP90AA1RAB9AALDH1A1MAPK1HPGD | |
| SCHEMBL11539203 | 0.74 | MEN1 (0.66) | RAB9AALDH1A1MAPK1KDM4ELMNA | |
| SCHEMBL9211562 | 0.72 | RAB9A (0.68) | RAB9AALDH1A1MAPK1HPGDLMNA | |
| SCHEMBL238772 | 0.72 | RXFP1 (0.51) | HSP90AA1RAB9AALDH1A1MAPK1HPGD | |
| Hydrochloric Acid SCHEMBL11534952 | 0.72 | MEN1 (0.69) | RAB9AALDH1A1KDM4EPOLBNPC1 | |
| SCHEMBL6270956 | 0.72 | ALDH1A1 (0.47) | RAB9AALDH1A1MAPK1HPGDKDM4E | |
| SCHEMBL11657490 | 0.70 | HSP90AA1 (0.50) | HSP90AA1RAB9AALDH1A1MAPK1HPGD | |
| SCHEMBL6927985 | 0.69 | RAB9A (0.43) | HSP90AA1RAB9AALDH1A1MAPK1HPGD | |
| Fopirtoline SCHEMBL287363 | 0.69 | RAB9A (0.49) | HSP90AA1RAB9AALDH1A1MAPK1HPGD | |
| SCHEMBL2669123 | 0.69 | RAB9A (0.44) | HSP90AA1RAB9AALDH1A1MAPK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056771-B1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-11-30 | — | — | EP | disclosed |
| EP-1056771-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043699-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION METHOD AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 1999-09-02 | — | — | WO | disclosed |